Cell Line Lysates
ABclonal Technology DYNLL1 Rabbit pAb
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
ABclonal Technology ZAK Rabbit pAb
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
World Precision Instrument Liquid Waveguide Capillary Cell, 500 cm pathlength
UV/VIS/NIR absorbance spectroscopy is governed by Beer’s Law, where the absorbance signal is proportional to chemical concentration, light path length and the compound’s specific molar absorption coefficient. Typical optical pathlengths of cuvettes and flow cells are between 0.2cm and 10 cm. Longer pathlengths are difficult to achieve due to mechanical constraints. Liquid Waveguide Capillary Cells (LWCCs) fill this gap. LWCCs are fiber optic flow cells that combine an increased optical pathlength (10–500 cm) with small sample volumes ranging from 2.4 µL to about 3mL. Compared with a standard 1cm cell, a 1 mAU signal is enhanced one hundred fold with a 100 cm flowcell to 100 mAU, using WPI’s patented aqueous waveguide technology.*
They can be connected via optical fibers to a spectrophotometer with fiber optic capabilities.
Abcam Human MYL6B (MLC1SA) knockout HEK-293T cell lysate.
Human MYL6B (MLC1SA) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TACC1 knockout HEK-293T cell lysate.
Human TACC1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human SLC25A40 knockout HEK-293T cell lysate.
Human SLC25A40 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology NFAT2 Rabbit pAb
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Abcam Human DR1 knockout HEK-293T cell lysate.
Human DR1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical AmIdepsIn A 2.5mg
A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 10.2 and 15.5 µM in rat liver microsomes and Raji cells, respectively
Abcam Human SYNJ1 (Synaptojanin) knockout HeLa cell lysate.
Human SYNJ1 (Synaptojanin) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical PIkromycIn 2.5mg
A macrolide antibiotic; active against E. coli, S. aureus, and B. subtilis (MIC99s = 50-60, 90-100, and 25-30 µM, respectively)
American Research Products Inc PrEST Antigen SLC2A1
PrEST Antigen SLC2A1 antigen APrEST87838 for solute carrier family 2 (facilitated glucose transporter) member 1 Recombinant protein fragment of Human SLC2A1
ABclonal Technology EEA1 Rabbit pAb
Enables 1-phosphatidylinositol binding activity, GTP-dependent protein binding activity, and protein homodimerization activity. Involved in endocytosis, vesicle fusion, and viral RNA genome replication. Located in cytosol and early endosome. Is extrinsic component of plasma membrane.
Cayman Chemical SultrIecIn 2.5mg
A fungal metabolite; active against a panel of 15 fungal strains (MICs = 0.8-50 μg/ml); cytotoxic to B16/F10, HCT116, Moser, P388, A549, and K562 cancer cells (IC50s = 37.7, 1.92, 0.85, 3.8, 4.14, and 0.67 μg/ml, respectively); inhibits RNA and protein synthesis in L1210 leukemia cells (IC50s = 5.5 and 2.4 μg/ml, respectively); increases survival time in a B16/F10 syngeneic mouse melanoma model and a P388 murine leukemia model from 0.1-10 mg/kg
Medchemexpress LLC Thy1/CD90 protein, human (HEK293) | >95.0% | 500 UG
Recombinant human Thy1/CD90 extracellular-domain protein produced in HEK293 cells, provided as a lyophilized, tag-free powder. The product corresponds to amino acids Q20-C130 of the human Thy1 sequence and is supplied with >95% purity by reducing SDS-PAGE; it is formulated in 20 mM PB, 150 mM NaCl (pH 7.4) prior to lyophilization and intended for research use only.